Developing community-based urine sampling methods to facilitate dietary exposure biomarker technology for population assessment

Proteomic methods for biomarker discovery in urine.

Many challenges exist with disease-state biomarker identification. These challenges include sample heterogeneity, poorly designed sample sets, insufficient numbers of samples, as well as inconvenient workflows, inadequate methodology, and development of false-positive markers resulting from protein degradation during sample handling. Yet despite these difficulties, substantial progress has been...

Exposure Assessment of the Tehran Population (Iran) to Zearalenone Mycotoxin

Zearalenone (ZEA) mycotoxin is a potent estrogenic metabolite. It is the primary toxin causing infertility, abortion or other breeding problems. A HPLC method was validated for ZEA in foods using a monolithic column with sample clean-up on an immunoaffinity column. A certified reference material (CRM) from FAPAS (UK) was analyzed. A survey of ZEA was performed on the 72 samples of rice, bread, ...

Exposure Assessment of the Tehran Population (Iran) to Zearalenone Mycotoxin

Zearalenone (ZEA) mycotoxin is a potent estrogenic metabolite. It is the primary toxin causing infertility, abortion or other breeding problems. A HPLC method was validated for ZEA in foods using a monolithic column with sample clean-up on an immunoaffinity column. A certified reference material (CRM) from FAPAS (UK) was analyzed. A survey of ZEA was performed on the 72 samples of rice, bread, ...

Burials: Dietary Sampling Methods

Dietary cadmium exposure assessment among the Chinese population

Cadmium, a toxic heavy metal, is widely present in food. It has been reported that chronic cadmium exposure is associated with kidney disease, osteoporosis, cardiovascular disease and cancer. The aim of this study was to assess the dietary cadmium exposure and potential health risk in different age-sex groups of the Chinese population (children aged 4-11 years, young people aged 12-17 years and...